There are many types of feed additives, some of which can cause antagonism when used simultaneously or in an excessive amount, causing the effect to be reduced or even lost. Therefore, when using feed additives, it must be noted that those that cannot be used at the same time, those that cannot be used in excess, prevent the occurrence of antagonism and cause unnecessary loss. Now we can analyze some feed additives that can produce antagonistic effects as follows:
Oxytetracycline should not be used simultaneously with calcium, magnesium, iron, tin, antimony and other elements, and its absorption can be inhibited, so that oxytetracycline loses its proper efficacy.
When adding iron, it is not advisable to add too much bone powder or calcium hydrogen phosphate, because the excessive amount of phosphorus can reduce the absorption of iron.
Excessive use of iron will accelerate the oxidative damage process of vitamins A, D, E, etc. in livestock and poultry.
Compounds such as iron, copper, manganese, zinc, and iodine can lower the potency of vitamins A, B1, B6, K3, and folic acid.
There is an antagonistic effect between calcium and zinc, so it is not advisable to add too much calcium when adding zinc sulfate. It is not advisable to add too much zinc sulfate when adding calcium.
When adding calcium hydrogen phosphate or bone meal, do not add too much magnesium oxide or magnesium sulfate, because too much magnesium can reduce the absorption of phosphorus.
When there is too much vitamin C, it can reduce the absorption and retention of copper in the body; the aqueous solution of vitamin C is acidic, and it has strong reducing property, which can reduce the effects of vitamins B1, B2, B12 and pantothenic acid.
Choline is very alkaline and can disable vitamins C, B1, B12, B6, K1, K2, and niacin and pantothenic acid.
Calcium and phosphorus are difficult to be absorbed or even absorbed in an alkaline environment. Therefore, calcium and phosphorus additives cannot be used simultaneously with alkaline choline.
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